Natalie, 44, is a single mother and lifestyle columnist living in Montreal. She sacrificed more exciting career options ten years ago, after her husband left her to raise their three children alone. Natalie’s an involved parent who loves her kids fiercely. She’s beaten kidney cancer once before, but her life is upturned when it comes back with a vengeance. Facing limited options, Natalie does her best to prepare her daughters for the future, a task complicated by the sudden return of their father David, who's suddenly seeking to prove himself to them. Determined to live in hope and fight her cancer, Natalie embarks on a clinical drug trial, while continuing to look for new ways to embrace life.