Canadians Milos Raonic and Eugenie Bouchard were both matched against unseeded opponents for the opening round of the U.S. Open in Thursday's draw.
Thornhill, Ont.'s Raonic, seeded fifth in the men's singles tournament, will face a to-be-determined qualifier in the opening round. He could meet Australian Open champion Stan Wawrinka in the quarter-finals.
Montreal's Bouchard, seeded No. 8 in the women's event, starts against unseeded Olga Govortsova of Belarus.
Bouchard has reached at least the semifinals at all three Grand Slam events so far this season, but has struggled since being trounced in July's Wimbledon final by Petra Kvitova, who is a potential quarter-final opponent at the U.S. Open.
Bouchard lost in the second round of the Connecticut Open this week as she battled a hamstring injury, but said she'll be ready to play in New York City next week.
Raonic, who made the semis at Wimbledon, reached the fourth round of the U.S. the last two years.
As for the other Canadians entries:
- Vasek Pospisil plays Italy's Simone Bolelli, with the winner potentially facing No. 16 Tommy Robredo in the second round.
- Frank Dancevic meets No. 32 Joao Sousa.
- Aleksandra Wozniak faces No. 31 Kurumi Nara.
- Sharon Fichman takes on No. 4 Agnieszka Radwanska.
Serena goes for 3rd straight title
Two-time defending women's champion Serena Williams will face American teen Taylor Townsend in the first round.
The 18-year-old Townsend is a former top-ranked junior player who reached the third round at the French Open this year. She got into her first U.S. Open main draw with a wild card.
Williams, who has won this event five times, could potentially play Wimbledon champion Kvitova in the semifinals. Second-seeded Simona Halep and the fourth-seeded Radwanska are in the other half. Halep could meet five-time major champ Maria Sharapova in the quarter-finals.
Wimbledon champ Novak Djokovic and Australian Open champ Stan Wawrinka could meet in one semifinal on the men's side. Second-seeded Roger Federer and fourth-seeded David Ferrer are in the other half. Djokovic could face Andy Murray in the quarter-finals.