The Expos released the hulking outfielder after he decided against accepting assignment to their minor-league affiliate, the triple-A Ottawa Lynx.
The Expos obtained Canseco, who is 38 homers short of the prestigious 500-homer club, in February after batting .258 with 16 homers and 49 RBI in 76 games with the Chicago White Sox.
After toiling with a number of teams in the American League as a designated hitter over the past decade, the 37-year-old was trying to prove that he can still play in the outfield.
Jose Canseco struggled in spring training with the Montreal Expos. (CP PHOTO)
But Canseco struggled at the plate in spring training, hitting .200 with three homers and five RBI in 14 games.
Canseco is best remembered during the early days of his career, when he teams with Mark McGwire to form the Bash Brothers with the Oakland A's.
He broke into the league in 1985 and instantly made an impression as a power hitter, slamming 29 homers and 117 RBIs to capture the American League Rookie of the Year award in 1986.
Two years later, he would make baseball history, becoming the league's first 40-40 man when he hit 42 homers and stole 40 bases. He won the MVP award for that memorable season.
But Canseco's temper and his habit of getting into injury trouble made him into a journeyman outfielder/designated hitter. Montreal was just the latest stop in an 18-year career that included Texas, Boston, Toronto, Tampa Bay, New York and Chicago.
Canseco resurrected his career in Toronto. After a sub-par year with the A's, Canseco joined the Blue Jays and reaffirmed his place as one of the best power hitters in the game by launching 46 homers, knocking in 107 RBIs and stealing 29 bases.
A six-time all-star, Canseco is 22nd all-time in career homers with 462. He is second among active players behind only Barry Bonds (567). He has hit more homers than any other player born outside the United States.