The total number of tests is about 50 higher than at past championships, the International Amateur Athletic Federation said Monday. About 17.5 per cent of the 2,000 athletes will be tested.
The testing will be monitored by independent observers of the World Anti-Doping Agency.
The IAAF said 15 to 20 per cent of the tests will be for EPO, or erythropoietin, a drug which stimulates the production of oxygen-rich red blood cells.
The EPO controls will involve testing of urine and blood samples. If the blood sample produces a positive finding, the urine will be analysed for confirmation.
A combined urine-blood EPO test was used for the first time during the Sydney Olympics, with no positive findings.
Scientists are still working to develop a foolproof, stand-alone urine test.
The IAAF said the majority of tests will be out-of-competition controls. In competition, the top three finishers will be tested, as will two others selected by random in each final. Athletes will also be tested at random during heats.
All the tests will be handled by the Canadian Centre for Ethics in Sport in conjunction with the IOC-accredited laboratory in Montreal.
