Barcelona's big three of Lionel Messi, Luis Suarez and Neymar all scored to beat Arsenal 3-1 on Wednesday, sending the defending champions into the Champions League quarter-finals for a ninth consecutive season with a 5-1 victory on aggregate.
Leading the tie after Messi scored both goals in a 2-0 first leg win, Suarez passed for Neymar to open the scoring in the 18th minute at Camp Nou.
Arsenal's Mohamed Elneny struck in the 51st, and the English side threatened to add another before Suarez answered with an acrobatic goal in the 65th.
Messi chipped in Barcelona's third with two minutes to play.
Barcelona increased its Spanish record streak to 38 unbeaten games, and stayed on course to repeat the treble of European Cup, Spanish league and Copa del Rey titles.
While Barcelona's march toward a season end that promises even more silverware, Arsenal coach Arsene Wenger has seen his side exit two of three competitions this week.
Arsenal bowed out of the FA Cup last weekend and now must focus on catching Tottenham and leader Leicester in the English Premier League standings.
Arsenal midfielder Mesut Ozil took the initiative during Barcelona's subdued start as a light rain came down over the Catalan capital.
But Messi, Neymar and Suarez quickly teamed up to put Barcelona into Friday's draw for the quarter-finals, taking the trio's combined tally to 106 goals this season.
Moments after Messi forced an excellent save by goalkeeper David Ospina, it was Suarez who caught Arsenal's backline in disarray. His diagonal pass left Neymar alone to slot a shot under Ospina, who touched the ball but couldn't keep it out.
Arsenal had its chances
Arsenal wasn't without its share of possession and shots, but a lack of finishing kept the visitors without a goal before halftime.
During a promising stretch, a glancing header by former Barcelona forward Alexis Sanchez bounced just by the far post of Marc-Andre ter Stegen's goal.
The English side found the net after the restart when Elneny blasted home a first-time strike from the edge of the area after Sanchez slid him the ball from the right side.
Danny Welbeck almost had a second goal for Arsenal after he got free on the break and appeared to have got the better of Javier Mascherno, only for Barcelona's last defender to recover in time and block his shot.
Suarez responded to the rally with an athletic strike that combined both power and finesse. Eyeing Dani Alves' cross, Suarez leapt, pivoted and struck the ball with his right shin to send it flying into the top corner.
Overturning the result was out of reach, but Arsenal continued to threaten.
Welbeck went close again with a shot that grazed the upright, and Ter Stegen was forced to make a one-handed save to block Sanchez's free kick before parrying substitute Olivier Giroud's attempt to put in the rebound with 10 minutes to play.
Messi rounded off the victory when he pounced on a deflected pass before lifting the ball over Ospina.
Barcelona also eliminated Arsenal from the Champions League knockout rounds in 2010 and 2011, after beating them in the 2006 final.
Bayern storms back against Juventus
Thomas Mueller equalized in the first minute of injury time and Bayern Munich scored two more goals in extra time to complete a thrilling comeback for a 4-2 victory over Juventus and a place in the Champions League quarter-finals.
Thiago Alcantara scored in the 108th minute to put Bayern ahead for good in the second leg match of the last 16 and Kingsley Coman, on loan from Juventus, added the German team's fourth in the 110th to give Bayern a 6-4 victory on aggregate. Bayern trailed 2-0 at halftime after goals from Paul Pogba and Juan Cuadrado, and the hosts looked to be on the way out until Robert Lewandowski scored in the 73rd, before Mueller's late header turned the match.