Eight types of drug
Most performance-enhancing drugs banned by the World Anti Doping
Agency's 2004 list of banned substances breaks down into eight categories. Click
on one to jump to the description or scroll to browse them all. For reference,
see also the drug dictionary.
Stimulants
WHAT ARE THEY?
Stimulants refer to a group of drugs that
boost alertness and physical activity by increasing heart and breathing
rates and brain functions. By acting on the central nervous system,
stimulants can stimulate the body both mentally and physically.
EXAMPLES adrafinil,
cocaine, modafinil,
pemoline, selegiline
WHY STIMULANTS ARE BANNED
They may artificially stimulate the mind
or body, thereby improving an athlete's performance and giving them
an unfair advantage.
WHY ATHLETES USE THEM To increase their ability to exercise at an optimal level, combat tiredness, suppress appetite.
TYPE OF PROHIBITION In-competition
EXCEPTIONS
Cathine is prohibited only when its concentration in a urine sample is greater than five micrograms per millilitre. Both ephedrine and methylephedrine are prohibited only when their concentration in a urine sample is greater than 10 micrograms per millilitre.
Narcotic analgesics
WHAT ARE THEY?
Narcotic analgesics usually take the form
of painkillers that act on the brain and spinal cord to treat pain
associated with painful stimuli.
EXAMPLES buprenorphine,
dextromoramide, heroin, morphine, pethidine
WHY THEY ARE BANNED Narcotic
analgesics could be used to reduce or eliminate the pain felt from
an injury or illness. They could also be used to help an athlete
train harder and for a longer period of time. The danger in this
is that the drug could merely be masking the pain. As a result,
athletes may have a false sense of security, and by continuing to
train and compete, risk further health problems.
WHY ATHLETES USE THEM To help reduce or eliminate the pain from a nagging injury, allowing them to continue in their training. Narcotic analgesics may also reduce anxiety, which may artificially enhance an athlete's performance.
TYPE OF PROHIBITION In-competition
EXCEPTIONS codeine,
dextromethorphan, dextropropoxyphene, dihydrocodeine, diphenoxylate,
ethylmorphine, pholcodine, propoxyphene, and tramadol
Cannabinoids
WHAT ARE THEY?
Cannabinoids are psychoactive chemicals derived
from the cannabis plant that cause a feeling of relaxation.
EXAMPLES hashish,
hashish oil, marijuana
WHY THEY ARE BANNED Marijuana
is generally not considered performance enhancing, but is banned
because its use is damaging to the image of sport. There are also
safety factors involved as the use of marijuana could weaken the
athlete's ability to perform, thereby compromising the safety of
the athlete and other competitors.
WHY ATHLETES USE THEM
To increase their recovery time after exercise, increase their heart rate, reduce their inhibitions.
TYPE OF PROHIBITION
In-competition
EXCEPTIONS The
WADA code requires each authority that adopts its list of banned
substances to determine for themselves whether to ban cannabinoids.
Where the rules of the drug testing authority specify, tests for
the presence of cannabinoids are conducted.
Anabolic agents
WHAT ARE THEY?
Anabolic Androgenic Steroids (AAS) are synthetic
versions of the hormone testosterone. Testosterone is a male sex
hormone found in large quantities in most males and in some females.
Anabolic Androgenic Steroids fall into one of two categories: 1)
exogenous steroids are those substances that are not capable of
being produced by the body naturally, and 2) endogenous steroids
are those substances that are capable of being produced by the body
naturally).
EXAMPLES exogenous
steroids (drostanolone, metenolone and oxandrolone), endogenous
steroids (androstenediol (andro), dehydroepiandrosterone
(DHEA) and testosterone)
WHY THEY ARE BANNED Anabolic
agents are prescribed for medical use only. Use of anabolic agents
may enhance an athlete's performance, giving them an unfair advantage.
Another possibility is serious medical side effects for the user.
WHY ATHLETES USE THEM
To increase muscle size and strength, reduce the amount of time required to recover after exercise, and to train harder and for a longer period of time.
TYPE OF PROHIBITION
In- and out-of-competition
EXCEPTIONS When
an athlete tests positive for an endogenous substance, his/her sample
is ruled to contain a prohibited substance where the concentration
of the substance in the sample is greater than the amount normally
found in humans. A sample will be ruled to not contain a prohibited
substance when the athlete proves with evidence that the excess
concentration of the endogenous substance in the sample is attributable
to a pathological or physiological condition. Both exogenous and
endogenous steroids, as well as their analogues (any substance derived
from modifying the chemical structure of another substance while
retaining a similar pharmacological effect) are prohibited.
Peptide hormones
WHAT ARE THEY?
Peptide hormones are substances that are
produced by glands in the body and that, after circulating through,
blood can affect other organs and tissues to change bodily functions.
EXAMPLES erythropoietin,
human
growth hormones, insulin,
corticotrophins
WHY THEY ARE BANNED Peptide
hormones serve as messengers between different organs that stimulate
various bodily functions such as growth, behaviour and sensitivity
to pain.
WHY ATHLETES USE THEM
To stimulate the production of naturally occurring hormones, increase muscle growth and strength, and increase the production of red blood cells to improve the blood's ability to carry oxygen.
TYPE OF PROHIBITION
In- and out-of-competition
EXCEPTIONS Chorionic
gonadotrophin, and pituitary and synthetic gonadotrophins are prohibited
in males only. Unless an athlete can demonstrate that the excess
concentration of the substance was due to a physiological or pathological
condition, his or her sample is ruled to contain a peptide hormone
where the concentration exceeds the amount normally found in humans.
Beta-2 agonists
WHAT ARE THEY?
Beta-2 agonists are drugs commonly used to
treat asthma by relaxing the muscles that surround the airway and
opening up the air passages.
EXAMPLES
bambuterol hydrochloride, reproterol hydrochloride, tulobuterol hydrochloride
WHY THEY ARE BANNED They
can provide the same advantages of a stimulant
or, if administered into the bloodstream, have anabolic
effects.
WHY ATHLETES USE THEM To
increase their muscle size and reduce body fat. When taken orally
or by injection, Beta-2 can have powerful stimulatory effects.
TYPE OF PROHIBITION
In- and out-of-competition
EXCEPTIONS Formoterol,
salubutamol, salmeterol and terbutaline are permitted by inhalation
only to prevent and/or treat asthma and exercise-related respiratory
problems. However, athletes need to provide a medical note in order
to attain a therapeutic-use exemption.
Masking agents
WHAT ARE THEY?
Masking agents are products that can potentially conceal the presence of a prohibited substance in urine or other samples.
EXAMPLES epitestosterone,
dextran, diuretics,
probenecid
WHY THEY ARE BANNED Masking
agents hide the presence of a banned substance in an athlete's urine
or other sample, allowing them to cover up their use and gain an
unfair competitive edge.
WHY ATHLETES USE THEM
To conceal their use of a prohibited substance in the testing process.
TYPE OF PROHIBITION
In- and out-of-competition
EXCEPTIONS Diuretics
(such as acetazolamide, mersalyl, and triamterene) are not prohibited,
so long as the athlete's urine sample contains amounts that don't
approach prohibited levels.
Glucocorticosteroids
WHAT ARE THEY?
In conventional medicine, glucocorticosteroids are used mainly as anti-inflammatory drugs and to relieve pain. They are commonly used to treat asthma, hay fever, tissue inflammation and rheumatoid arthritis.
EXAMPLES
dexamethasone, fluticasone, prednisone, triamcinolone acetonide and rofleponide
WHY THEY ARE BANNED
When administered systemically (into the blood) glucocorticosteroids can produce a feeling of euphoria, potentially giving athletes an unfair advantage.
WHY ATHLETES USE THEM
To mask pain felt from injury and illness.
TYPE OF PROHIBITION
In-competition
EXCEPTIONS Glucocorticosteroids
are prohibited when administered orally, rectally, or by intravenous
or intramuscular administration. All other administrations require
the athlete to provide a medical note in order to attain a therapeutic-use
exemption.