In a lost season for the New York Giants, a concussion kept Victor Cruz from reaching a personal milestone.
The team's top receiver was injured in the fourth quarter of a 23-0 loss to the Seattle Seahawks on Sunday.
Cruz left 2 yards short of his third straight 1,000-yard season. He caught two passes for 25 yards before getting hurt.
The Giants (5-9) have two games left. They are stuck with their first losing year since 2004.
Cincinnati punter Kevin Huber left Sunday night's game after taking a hard hit from Pittsburgh's Terence Garvin on a 67-yard kick return for a touchdown by Antonio Brown.
Huber was down on the field for several minutes. His mouth was bloody as he walked to the Bengals' locker room with what the team called a "dental injury."
Bengals linebacker James Harrison, making his first appearance in Pittsburgh since signing with the Bengals in the off-season, left in the first quarter because of a concussion.
The Dallas Cowboys and Green Bay both lost players in the Packers' 37-36 win.
Starting defensive end Johnny Jolly came out with a shoulder injury in the first half. He didn't return.
Packers tight end Brandon Bostick also left with a foot injury.
After Dallas starting linebacker Justin Durant exited with a hamstring, backup linebacker Ernie Sims needed X-rays when he hurt his left hip on the final play of the first half.
Jacksonville backup guard Mike Brewster broke his left ankle in the Jaguars' 27-20 loss to Buffalo.
The Cleveland Browns lost star cornerback Joe Haden in the second half with a hip pointer. His absence allowed Chicago quarterback Jay Cutler to pick on rookie cornerback Leon McFadden in the Bears' 38-31 win.