Michelle Wie was stung by a bee Thursday in the season-opening Pure Silk-Bahamas LPGA Classic, and second-ranked Inbee Park withdrew because of back pain after the second-worst round of her LPGA Tour career.

Wie was stung on the palm of her right hand on the 16th hole, her seventh of the day at the windy Ocean Club. She finished with a 3-over 76 to fall eight strokes behind first-round leaders Paula Creamer, Charley Hull, Alison Lee, Ashlan Ramsey, Catriona Matthew, Mika Miyazato and Haru Nomura.

"I was waiting to hit my tee shot and I felt something sting and it hurt really, really bad and I knew it was a bee," Wie said from Paradise Island. "I brushed it away and the stinger was still in there. We were trying to find a tweezer and out of all the people, our security guy had tweezers on him, so I got it out."

Brooke Henderson of Smiths Falls, Ont., was the top Canadian at 2-under, tied for 18th place and three shots off the pace. Maude-Aimee Leblanc of Sherbrooke, Que., and Hamilton's Alena Sharp are tied for 45th at even-par.

Wie bogeyed three of the first five holes on her back nine.

"It just kind of felt so swollen it was kind of hard to grip the club. I was hitting the ball so well on the front nine and just definitely had a couple loose ones coming in making the turn. You can kind of feel the venom kind of spread. But the last couple holes, it's feeling better."

She struggled with her putting.

"I only missed two greens," Wie said. "I just putted horribly."

Park shot an 80, playing her final four holes in 5 over with a double bogey on the par-5 15th and three bogeys. She will sit out the Coates Golf Championship next week in Florida, and hopes to return late next month in the Honda LPGA Thailand.

Creamer played a late three-hole stretch in 4 under, making an eagle on the par-4 eighth.

Lee finished with a bogey on the par-4 ninth after playing the previous three holes in 4 under with an eagle on the par-5 seventh. She is still a student at UCLA.

Miyazato had only 10 putts in a first-nine 6-under 31.

Jennifer Johnson and Min Seo Kwak were a stroke back at 69.

Defending champion Sei Young Kim opened with a 71, and 2014 winner Jessica Korda had a 72. Third-ranked Stacy Lewis shot 73, No. 4 Lexi Thompson 74, and No. 11 Christie Kerr 77.