Wichita State 76, Gonzaga 70

Gonzaga's gone.

Cleanthony Early and Ron Baker scored 16 points apiece and Wichita State hit a season-high 14 3-pointers, including seven straight late, to knock the top-ranked and No. 1 seeded Bulldogs out of the NCAA tournament 76-70 on Saturday.

The Shockers (28-8) advanced to the Round of 16 for the first time since 2006, while Gonzaga becomes the first top seed to be eliminated.

Gonzaga survived a scare in the second round against Southern but couldn't hold up against a fellow mid-major from Kansas whose motto is "play angry."

The Shockers face the winner of Sunday's game between La Salle and Ole Miss.

Wichita State had the Zags down 13 early. Though Gonzaga (32-3) fought back, the barrage of 3s was too much for the small school from Spokane, Wash.

Canadian Kelly Olynyk scored 26 points to lead Gonzaga, and countryman Kevin Pangos had 19.

Syracuse 66, California 60

C.J. Fair scored 18 points, James Southerland added 14 and fourth-seeded Syracuse survived a second-half drought of more than 12 minutes without a field goal to beat No. 12 seed California 66-60 on Saturday night and advance to the round of 16 in the NCAA tournament.

The Orange (28-9) frustrated California with their zone defence to overcome a dismal shooting night when they made just 39 per cent of their shots and missed 15 of 41 free throws.

But it proved to be enough to send Syracuse to Washington, D.C., for the East Regional where the Orange will take on the winner of Sunday's game between top-seeded Indiana and Temple on Thursday.

Richard Solomon scored 22 points for the Golden Bears (21-12), who were trying to make it to the round of 16 for the first time in 16 years and just the third time since 1960.

Michigan State 70, Memphis 48

Michigan State is into the round of 16 for the NCAA tournament — as usual.

Gary Harris scored 16 of his career-high 23 points in the first half and the third-seeded Spartans cruised past sixth-seeded Memphis 70-48 on Saturday, putting the Tom Izzo-led program in the regional semifinals for the fifth time in six years and the 11th time in his career.

Michigan State (27-8) will play the winner of the Duke-Creighton game on Friday in the Midwest Regional semifinals at Lucas Oil Stadium in Indianapolis.

The Tigers (31-5) advanced in the NCAA tournament for the first time in Josh Pastner's four seasons. The Conference USA champions are headed home because they struggled to stop Harris on the outside or his teammates inside all afternoon.

The Spartans' top post players — Adreian Payne and Derrick Nix — combined for 27 points and 18 rebounds.

Michigan 78, Virginia Commonwealth 53

Michigan made Havoc look helpless.

Now Trey Burke, Tim Hardaway Jr. and the rest of the cool-headed Wolverines are part of the school's longest NCAA tournament run in nearly two decades.

Mitch McGary had 21 points and 14 rebounds, and fourth-seeded Michigan breezed through Virginia Commonwealth's vaunted pressure with a clinical performance Saturday, beating the fifth-seeded Rams 78-53 to advance to the regional semifinals for the first time since 1994.

VCU couldn't create many easy baskets with its press, even though the Wolverines didn't have much time to prepare for it.

McGary, a 6-foot-10 freshman, set season highs in scoring and rebounding. VCU had no answer for him around the basket, and that pressure defence — the Rams call it "Havoc" — wasn't much of a factor.

VCU was relentless in a 46-point rout of Akron on Thursday night, but the Rams met their match against Michigan's backcourt. Burke and Hardaway rarely looked rattled, and Michigan (28-7) committed only 12 turnovers.

The 71-point swing by VCU — from a 46-point win to a 25-point loss — was the largest in NCAA tournament history, according to STATS. In 1968, Houston beat Texas Christian 103-68 to reach the Final Four, then lost to UCLA 101-69 for a 67-point swing.

VCU (27-9) went 0-8 this season when forcing under 15 turnovers.

McGary made his first seven shots from the field. Burke scored 18 points, Hardaway and Glenn Robinson III added 14 each, while Nik Stauskas of Mississauga, Ont., chipped in with eight points and three rebounds.

Juvonte Reddic scored 16 points for VCU.

Arizona 74, Harvard 51

For Arizona, it's on to Los Angeles. And for Harvard, well, it's time to head back to class.

Clearly unfazed by their Ivy League opponent's plucky brand of Smartball, the Wildcats showed how a real basketball school does it Saturday. Mark Lyons matched his career high with 27 points in Arizona's wire-to-wire 74-51 blowout of the Crimson.

No. 6 seed Arizona's next stop in the NCAA tournament is southern California, where the Wildcats will make their 15th appearance in the regional semifinals. They'll play the winner of Sunday's game between Ohio State and Iowa State.

The day for No. 14 Harvard (20-10) was best summed up early in the second half when point guard Siyani Chambers took an elbow to the mouth from Kevin Parrom, who chipped off part of Chambers' front tooth. Officials stopped play and Chambers' teammate, Christian Webster, walked over, bent down and picked up the tooth fragment off the floor.

That felt nothing like Thursday, when Harvard pulled off an upset over a physically imposing New Mexico team, a stunner that riled up the Harvard twitterrati and sparked dreams of nets somehow being cut down with a slide rule. Yes, Tommy Amaker's program could be redefining what's possible in the Ivy League.

But Arizona (27-7), a team that hasn't lost to an opponent outside of the Pac-12 this season, had too much height, too much speed, too much talent to be slowed by this Harvard team.

Louisville 82, Colorado State 56

Russ Smith had another big night, leading four players in double figures with 27 points, and top-seeded Louisville is into the Midwest Region semifinals.

The Cardinals put on a defensive clinic as they dismantled Colorado State 82-56 on Saturday. Louisville forced the eighth-seeded Rams into a season-high 20 turnovers, made Colton Iverson look as invisible as a 6-foot-10 guy can be and limited one of the nation's best rebounding teams to 24 boards, more than a dozen below their average.

It was the 12th straight win for Louisville (31-5), which will play Oregon on Friday in Indianapolis.

Oregon 74, Saint Louis 57

Oregon is riding its much-debated No. 12 seed all the way to the round of 16.

Damyean Dotson scored 23 points, Carlos Emory added 14 points and the hot-shooting Ducks sprinted past fourth-seeded Saint Louis 74-57 in the NCAA tournament Saturday night.

Dotson made his first five 3-pointers to carry Oregon (28-8) into the second weekend for the first time since 2007, when it lost to eventual repeat champion Florida in the regional final. The Ducks made 8 of 11 shots from beyond the arc, while the Billikens finished 3 for 21 from long range.

Oregon will play No. 1 overall seed Louisville in the Midwest Regional in Indianapolis next. The Cardinals routed Colorado State 82-56 in Lexington, Ky.

Marquette 74, Butler 72

Vander Blue scored 19 second-half points to rally third-seeded Marquette out of another hole, and the Golden Eagles survived No. 6 Butler 74-72 on Saturday to reach the Round of 16.

Like November's first meeting between the teams at the Maui Invitational, won 72-71 by Butler on Rotnei Clarke's buzzer-beating 3-pointer, this was a back-and-forth, high-intensity affair, that came down to the final shot. Only this time, Butler missed.

Marquette (25-8) will meet the winner of Sunday's game between Illinois and Miami (Fla.) on Thursday in Washington, D.C.

Clarke's 24 points led Butler (28-9).

Blue, the junior whose last-second layup edged Davidson on Thursday, led the Golden Eagles' rally from a 35-27 halftime deficit and tied the game at 69 on 3-pointer with 1:25 remaining.