Here's what's happening on the second day of the NCAA men's basketball tournament:

(15) Middle Tennessee State, (2) Michigan State

No. 15 seed Middle Tennessee State sent the biggest shock yet through the NCAA Tournament on Friday, topping second-seeded Michigan State 90-81 in the first round.

Reggie Upshaw scored 21 points to lead the balanced Blue Raiders (25-9), who shut down player of the year candidate Denzel Valentine. Middle Tennessee never trailed the Spartans (29-6) in one of the biggest upsets since the tournament began seeding teams in 1985.

It was the eighth time a No. 2 seed beat a No. 15, and first since Florida Gulf Coast beat Georgetown in 2013. The Eagles went on to reach the Sweet 16.

(14) Stephen F. Austin 70, (3) West Virginia 56

Thomas Walkup scored 33 points and 14th-seeded Stephen F. Austin faced down West Virginia's full-court pressure with some of its own in-your-face defence, pulling off a rugged, 70-56 first-round upset of the third-seeded Mountaineers Friday night.

The Lumberjacks (28-5) ran the nation's longest winning streak to 21 games and will face either six seed Notre Dame or No. 11 Michigan on Sunday at Barclays in the second round of the East Region.

The Mountaineers (26-9) and Lumberjacks played physical, chest-to-chest defence, contesting not just every shot, but every pass. Neither team shot better than 31 per cent.

(1) Oregon 91, (16) Holy Cross 52

Carrying the marquee for the underachieving Pac-12, No. 1 seed Oregon showed no nerves playing as a top seed and rolled past No. 16 seed Holy Cross 91-52 on Friday night in a West Regional first-round game.

Chris Boucher led Oregon (29-6) with 20 points as the Ducks won their ninth straight and advanced to the round of 32 for the fourth straight season.

With nearly all of the Pac-12 making a quick exit out of the NCAA Tournament, the Ducks used their overwhelming athleticism to quickly build a double-digit lead and never allowed the Crusaders to sniff a potential 16-seed upset.

(11) Northern Iowa 75, (6) Texas 72

Paul Jesperson banked in a halfcourt shot at the buzzer to give 11th seeded Northern Iowa a 75-72 win over No. 6 seed Texas Friday night.

Northern Iowa passed the ball in under its basket after Isaiah Taylor tied the game on a layup with 2.7 seconds to play. Jesperson caught the ball, took a few dribbles and heaved.

Wes Washpun scored 17 points and Jesperson added 14 for the Panthers (23-12), who claimed their fifth NCAA Tournament win in school history.

(10) Syracuse 70, (7) Dayton 51

Malachi Richardson scored 21 points, Syracuse stumped seventh-seeded Dayton with its trademark zone and the No. 10 seed Orange rolled to a 70-51 victory in their return to the NCAA Tournament on Friday.

Tyler Roberson added 10 points and 18 rebounds for the Orange (19-13), banned from the field last season following an NCAA investigation into academic misconduct and improper benefits.

Tyler Lydon had 14 points, Trevor Cooney had 13 and Michael Gbinije added 10 as Syracuse advanced to play No. 2 seed Michigan State or No. 15 seed Middle Tennessee State on Sunday.

(13) Hawaii 77, (4) California 66

Hawaii won its first NCAA Tournament game in school history when the 13th-seeded Warriors ended No. 4 California's tumultuous week with a 77-66 upset victory Friday in the first round of the South Regional.

Quincy Smith scored a career-high with 19 points, Roderick Bobbitt had 17 points and Stefan Jankovic of Mississauga, Ont., 16 for the champions of the Big West Conference regular season and tournament. Hawaii (28-5) used a strong first half from Jankovic to lead by as many as 11, then withstood Jankovic's foul trouble in the second half thanks largely to Smith.

The Warriors were 0-4 in their previous NCAA appearances, the last coming in 2002.

(2) Oklahoma 82, (15) Cal State Bakersfield 68

Buddy Hield scored 27 points to help No. 2 seed Oklahoma defeat No. 15 seed Cal State Bakersfield 82-68 Friday in the first round of the NCAA Tournament. The senior guard made 8 pf 14 shots, including 3 of 6 3-pointers.

Isaiah Cousins scored 16 points and Jordan Woodard added 15 for the Sooners (26-7), who made 11 of 20 3-pointers and shot 50 percent overall.

The Sooners advanced to play No. 10 seed Virginia Commonwealth, which defeated Oregon State 75-67 earlier in the day. Aly Ahmed had 16 points and eight rebounds for Bakersfield (24-9), the Western Athletic Conference Tournament champions.

(2) Xavier 71, (15) Weber State 53

James Farr had 18 points and 15 rebounds, fellow big man Jalen Reynolds added 12 points and Xavier pulled away late for a victory over pesky Weber State.

Remy Abell added 11 points and Trevon Bluiett had 10 for the Musketeers (28-5), who never trailed the Big Sky Tournament champs.

Weber State (26-9) was within 54-47 midway through the second half when Farr and Reynolds, both of them heftier than anybody on the Wildcats' bench, began to impose their will. The managed to power right through Weber State's back line for easy buckets, allowing the Musketeers to slowly draw away.

(8) Saint Joseph's 78, (9) Cincinnati 76

Isaiah Miles sank a 3-pointer with nine seconds left to lift Saint Joseph's to a 78-76 win over Cincinnati after a dunk at the buzzer by the Bearcats was waved off.

Octavius Ellis appeared to tie the game with his dunk as time expired, but officials after a lengthy review determined that the shot came too late.

DeAndre Bembry scored 23 points and Miles finished with 19 to lead eighth-seeded Saint Joseph's (28-7). Twenty of Bembry's points were in the first half.

(3) Texas A&M 92, (14) Green Bay 65

Danuel House scored 20 points as Texas A&M pulled away in the second half to win its first NCAA Tournament game since 2010 with a first-round victory over Green Bay.

The third-seeded Aggies (27-8) trailed by as many as eight points in the first half before using a 26-9 first-half run to take control on the way to a comfortable victory.

House was 8 of 12 from the field and hit a pair of 3-pointers for Texas A&M, which shot 56.1 per cent (32 of 57) in the win. Khalil Small scored a career-high 22 points to lead the Horizon League Tournament champion Phoenix (23-13), who were making their first tournament appearance in 20 years.

(6) Notre Dame 70, (11) Michigan 63

V.J. Beacham scored 18 points, including the 3-pointer that gave Notre Dame the lead for good, and the Fighting Irish beat Michigan.

The Fighting Irish (22-11) didn't take a lead in the game until Beacham's 3 with 9:26 left to make it 51-48. From there on there were five lead changes and three ties. Beacham's 3 with 4:24 left gave Notre Dame a 62-59 lead, one they never gave up.

Michigan (23-13) controlled the first half, taking a 41-29 lead.

(5) Maryland 79, (12) South Dakota St. 74

Maryland needed a turnover in the closing seconds to ensure it would avoid a place with all the other top seeds that lost in the first round of this topsy-turvy NCAA Tournament, holding off South Dakota State 79-74 Friday behind a career-high 27 points from Jake Layman.

Melo Trimble added 19 points and Jared Nickens 14 for fifth-seeded Maryland (26-8).

South Dakota State was seeking its first victory in the NCAA Tournament, but was undone by cold shooting in the first half.

(7) Wisconsin 47, (10) Pittsburgh 43

Ethan Happ had 15 points and nine rebounds, none bigger than one he pulled down in the closing seconds, as seventh-seeded Wisconsin beat No. 10 seed Pittsburgh 47-43 on Friday night.

Nigel Hayes had 12 points and Vitto Brown scored 11 for the Badgers (21-12), who advanced despite an awful shooting night. Hayes was just 3 for 17 from the field, Bronson Koenig failed to hit a 3-pointer for the first time in 44 games and the Badgers finished 4 of 19 from beyond the arc.

Wisconsin will play No. 2 seed Xavier or No. 15 seed Weber State on Sunday.

(7) Iowa 72, (10) Temple 70

Adam Woodberry put back a missed shot at the overtime buzzer to give Iowa a 72-70 victory over Temple on Friday in the first round of the South Regional at Barclays Center.

With the game tied at 70, Mike Gesell worked his way to the baseline and put up about a 10-foot jumper that missed the rim and went right to Woodberry, who put it in as the red lights around the backboard lit up.

The Hawkeyes got the chance at the game-winner when Daniel Dingle of Temple, who played just six minutes and was in the game because Devin Coleman had fouled out a minute earlier, missed the front end of a one-and-one.

(2) Villanova 86, (15) UNC Asheville 56

Ryan Arcidiacono scored 14 points, including a buzzer-beating 3 at the end of the first half, and Daniel Ochefu had 17 points inside as second-seeded Villanova beat UNC Asheville 86-56 Friday to roll into the second round of the NCAA Tournament.

Dylan Smith led 15th-seeded UNC Asheville (22-12) with 14 points as the Big South champions bowed out quietly.

Kris Jenkins scored 12 and Jalen Brunson had 10 points for the Villanova, which spent three weeks at No. 1 this season but is under pressure to return to the Sweet 16.

(10) VCU 75, (7) Oregon State 67

JeQuan Lewis had 21 points, eight assists and seven rebounds as 10th-seeded Virginia Commonwealth won its first NCAA Tournament game since 2013 with a 75-67 first-round victory over No. 7 seed Oregon State on Friday.

The tournament appearance is the sixth straight for VCU (25-10), and the experience showed as the Rams led by eight points at halftime and held off a charge by the Beavers in the second half.

Mo Alie-Cox added 20 points and was 7 of 8 from the field in the win, while Melvin Johnson also finished in double figures with 12 points. Gary Payton II scored 19 points to lead the Beavers (19-13), who were making their first tournament appearance in 26 years, while Derrick Bruce finished with 15 and Drew Eubanks 13.