Toronto right-hander Dustin McGowan has pitched his second simulated game, throwing 44 pitches over two innings.
Barring any right shoulder soreness in the next two days, he expects to throw 50 to 60 pitches Friday in a game against Blue Jays minor leaguers.
McGowan last pitched in a regular-season game July 8, 2008, before undergoing shoulder surgery to repair a torn labrum. He sat out the 2009 season because of setbacks in rehabilitation, one requiring left knee surgery. He is likely to start the season on the disabled list.