The Boston Red Sox say Grady Sizemore will start in centre field on opening day, completing his comeback from a series of injuries that almost ended his career.

The three-time All-Star is set to start for the World Series champions on Monday at Baltimore.

Sizemore has not played in the majors since September 2011 with Cleveland. He has undergone seven surgeries since 2009, including operations on both knees, his back and elbow.

The Red Sox lost star center fielder Jacoby Ellsbury to the Yankees in free agency during the offseason. Boston signed the 31-year-old Sizemore in January, hoping he could still make an impact.

Sizemore hit .333 in spring training and held up well in the outfield.

Sizemore beat out highly regarded prospect Jackie Bradley Jr. for the starting job. The Red Sox said Friday that Bradley will begin the season at Triple-A Pawtucket.