Brown missed last season with a knee injury after a strong 2012 campaign. He tore his left anterior cruciate ligament in a preseason game against the Jets and underwent surgery two weeks later.
The 27-year-old Brown, who led the Giants with eight interceptions last season, was placed on injured reserve on Sunday. For now, it leaves the Giants without the starting safeties from a year ago, with strong safety Antrel Rolle still out with a sprained ankle.
Brown, who led the team with eight interceptions last season, tied for second in the NFL, appeared to be hurt when he was tackled after a 22-yard return. The four-year veteran could not put any weight on his leg.
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