Hillis got the nod over recently activated Andre Brown after the Giants announced Sunday that Brandon Jacobs would miss the game with hamstring and knee problems. Jacobs had been listed as doubtful.
Hillis made his Giants debut as he learned what it is like running behind one of the worst offensive lines in pro football.
Hillis, who fills a void in the backfield, is a six-year veteran with a 1,000-yard season on his resume. He has played for Denver, Cleveland and Kansas City, and has 2,470 yards and 21 touchdowns for his career. Hillis has played in 65 games with 33 starts, and has also caught 111 passes for 867 yards. In 2010, he had a career season while playing for Cleveland. He ran for 1,177 yards, with 11 touchdowns, on 270 carries, and played in all 16 games.