The once reliable quarterback has seven interceptions in his last two games and 10 this season. He's four shy of matching his career high with seven games left, but he's still might have a chance to rack up yards for the struggling Falcons.
Ryan came within one pick of his career high of five, which also came against the Cardinals in 2012.
Ryan completed 20 of 26 passes for 273 yards with three touchdowns and no interceptions. He faces the Cards next weekend.
Ryan has thrown two TD passes in each game compared to three turnovers. He's still a No. 1 fantasy QB despite the Falcons' 1-4 start.
Ryan's previous high was 411 yards in a loss at New Orleans on Nov. 11, 2012. He's completed 69.1 percent of his attempts for 795 yards with four scores and one pick in two home games. He's thrown for 535 passing yards in a pair of road losses.
Ryan has thrown two TDs in each game this season and remains a must-start regardless of the matchup.
Ryan's 2013 campaign is off to a fine start as he's totaled 678 yards and four TDs through his first two contests.
Ryan has thrown for 1,598 yards with 13 touchdowns and two interceptions over his last six regular-season games dating back to last season.
A person familiar with the situation says Ryan's extension is for $103.75 million deal, with $59 million guaranteed. The person says Ryan will average $20.75 million during the first three years of the extension. The person spoke to The Associated Press on condition of anonymity because the terms of the deal had not been announced. Ryan, 28, is entering the sixth and final season of his original rookie contract and will earn a $10 million salary.
General manager Thomas Dimitroff says he hopes to have a new deal with Ryan before the season. The quarterback's six-year, $66 million contract expires after the 2013 season. Ryan says he's confident Dimitroff and his agent, Tom Condon, "will get that stuff done."