Donald Trump's supporters may stand behind him after his proposed Muslim immigrant ban, but there's evidence the Republican presidential frontrunner's latest controversial remarks have damaged his political and business career. 

It's not yet clear whether Trump's remarks will hurt him in the polls, but he has a history of maintaining popularity amid controversy, staying at the head of the pack after making disparaging remarks about women and Mexicans

What's more, a recent Associated Press-Gfk poll suggests many Americans share his fears about immigration, with 54 per cent saying the U.S. takes in too many people from the Middle East. 

Still, Trump's comments have drawn rebuke from both ends of the political spectrum and around the world from business and political leaders, many of whom he might someday need on his side.

Here are five ways Trump is facing fallout over his inflammatory comments.

1. He could get banned from U.K.

The man who wants to be the president of the United States faces a potential ban from one of his country's oldest and most powerful allies.

While defending his proposal to ban Muslim immigration to the U.S. on Tuesday, Trump invoked London as an example of the consequences of Islamic extremism, saying: "We have places in London and other places that are so radicalized that the police are afraid for their own lives."

The comments drew repudiation from London's mayor and police chief, as well as British Prime Minister David Cameron. An online signature calling for Trump to be banned from entering the U.K. surpassed 10,000 signatures in less than 24 hours, which means the U.K. Parliament has to debate the issue. 

Tory MP Sarah Wollaston has said there will "certainly be a discussion" about banning the business mogul on the same grounds used to bar a number of Islamic extremists as well as anti-Muslim bloggers Pamela Geller and Robert Spencer, the Express newspaper reports.

Leading U.K. think-tank British Future has issued a statement urging the country to consider the ban. 

2. He's alienating American allies

The British aren't the only ones expressing scorn for Trump's proposals. His comments have drawn the ire of many leaders of nations and international institutions that work closely with the United States.

"Canadians soundly rejected the politics of fear and division," Prime Minister Justin Trudeau said. 

British Prime Minister David Cameron, breaking the custom of British leaders not commenting on U.S. presidential contenders, slammed Trump's plan as "divisive, unhelpful and quite simply wrong."

A UN spokesman said Secretary General Ban Ki-moon denounced "any kind of rhetoric that relies on Islamophobia, xenophobia, any other appeal to hate any groups."

In France, where co-ordinated attacks by Islamic extremists killed 130 people last month, Prime Minister Manuel Valls tweeted: "Trump, like others, stokes hatred and conflations. Our only enemy is radical Islamism."

3. He's run afoul of Pentagon

Trump also runs the risk of entering the Oval Office without the support of the country's top defence officials. His proposed Muslim immigrant ban drew a sharp rebuke from the Pentagon on Tuesday, with press secretary Peter Cook suggesting the policy would jeopardize national security.

"Anything that bolsters ISIL's narrative and pits the United States against the Muslim faith is certainly not only contrary to our values but contrary to our national security," Cook said, using an acronym for the Islamic State in Iraq and Syria.

Homeland Security Secretary Jeh Johnson also said Trump's proposal could thwart U.S. efforts to connect with the Muslim community.

4. He's plunging his party into chaos

If Trump secures the presidency, he may face opposition not just from Democrats but from his own party, too.

An internal report by Republican strategists after Mitt Romney's loss to Barack Obama in 2012 concluded that in order to stay relevant, the party must appeal to black, Hispanic, and Asian American voters.

Most of Trump's Republican presidential rivals have condemned his statements.  

Senator Lindsey Graham, a leadership rival, said Trump's rhetoric could inflame tensions in the Middle East.

"He's putting our soldiers and diplomats at risk; he's empowering the enemy," Graham told CNN.

GOP 2016 When to Drop Out

Senator Lindsey Graham says Trump's comments put Americans at risk. (Nati Harnik/Associated Press)

Other established Republicans — including  House Speaker Paul Ryan, Republican National Committee chairman Reince Priebus and former U.S. vice-president Dick Cheney — have also spoken out against Trump.

5. He's losing business deals 

Trump prides himself on his business acumen, but his recent comments have soured some of financial relationships and put his overall brand in jeopardy.

Landmark Group, one of the Middle East's largest retail firms, told the Independent newspaper it is cutting ties with Trump.

"We have suspended sale of all products from the Trump Home decor range," Lifestyle chief executive Sachin Mundhwa said in an email to the British newspaper.

City councillors and planners in Vancouver and Toronto are pushing to change the names of their respective Trump Tower hotel-condominums. 

Toronto Coun. Josh Matlow tweeted: "Toronto is a diverse and respectful city. Donald Trump is a fascist."

Vancouver Trump Tower

City councillors and planners are pushing to change the name of Vancouver's Trump Tower. (Holborn Group)

With files from Reuters and Associated Press