A powerful earthquake Wednesday off the Solomon Islands generated a small tsunami that damaged dozens of homes and left several people missing and presumed dead in the South Pacific island chain.

Authorities cancelled tsunami warnings on more distant coasts.

Solomons officials reported two 1.5-metre waves hit the western side of Santa Cruz Island, damaging between 70 and 80 homes and properties, said George Herming, a spokesman for the prime minister. Many villagers had headed to higher ground as a precaution, Herming said.

Solomon Islands Police Commissioner John Lansley said local police patrols reported that several people were presumed dead, though the reports were still being verified.

"Sadly, we believe some people have lost their lives," he said. "At the moment we potentially know of four, but there may of course be more."

Early Wednesday morning, forecasters with Japan's Meteorological Agency issued a large-scale tsunami advisory covering the country's entire Pacific coastline. The forecasters say a tsunami of 50cm could come ashore between 4:30 p.m. and 6:00 p.m. Japan time (2:30-4:00 p.m. ET). They are telling people to stay away from the ocean, the coast and the mouths of rivers.

Several presumed dead

One of the people presumed dead in the Solomon Islands was fishing in a dugout canoe when the first wave hit, sweeping him out to sea, Herming said. Officials were searching for his body. Another woman was believed to have drowned when the water rushed into her village, Herming said.

Four villages on Santa Cruz were hit by the waves, with two facing severe damage, Lansley said. Other areas of the Solomons did not appear to have been seriously affected.

Dozens of homes were damaged in the area of Lata, Temotu province following the earthquake (World Vision/Associated Press)

Disaster officials were struggling to reach the remote area after the tsunami flooded the airstrip at the nearest airport and left it littered with debris.

The tsunami formed after a magnitude-8.0 earthquake struck near the town of Lata, on Santa Cruz in Temotu, the easternmost province in the Solomons, about a three-hour flight from the capital, Honiara. Temotu has a population of around 30,000.

The Pacific Tsunami Warning Center said a tsunami of about a metre was measured in Lata wharf. Smaller waves were recorded in Vanuatu and New Caledonia.

Residents head to higher ground

Richard Dapo, a school principal on an island near Santa Cruz, said he lives inland but has been fielding calls from families on the coast whose homes have been damaged by the waves.

"I try to tell the people living on the coastline, 'Move inland, find a higher place. Make sure to keep away from the sea. Watch out for waves,"' he said.

He said he heard the waves swamped some smaller islands, although he was not aware of any deaths or serious injuries. He said it was difficult to contact people because cellphone coverage was patchy in the region.

In Honiara, the warnings prompted residents to flee for higher ground.

"People are still standing on the hills outside of Honiara just looking out over the water, trying to observe if there is a wave coming in," said Herming, the prime minister's spokesman.

Atenia Tahu, who works for the Solomon Islands Broadcasting Corp. in Honiara, said most people were remaining calm.

"People around the coast and in the capital are ringing in and trying to get information from us and the National Disaster Office and are slowly moving up to higher ground," Tahu said. "But panic? No, no, no, people are not panicking."

Hospital taking precautions

Dr. Rooney Jagilly, the medical superintendent at the National Referral Hospital in Honiara, said the hospital asked about half its 200 patients to leave and stay with families or friends as a precautionary measure because the hospital is located near the shoreline. Those patients who weren't mobile enough to move stayed, but the hospital remained ready to evacuate them.

Jagilly said there had been no flooding and he hoped the hospital would return to normal Thursday. He said his staff was ready to mobilize to Santa Cruz because the small hospital there has no doctor after the previous one recently died.

An official at the disaster management office in Vanuatu said there were no reports of damage or injuries there.

More than 50 people were killed and thousands lost their homes in April 2007 when a magnitude-8.1 quake hit the western Solomon Islands, sending waves crashing into coastal villages.

The Solomons comprise more than 200 islands with a population of about 552,000 people. They lie on the "Ring of Fire" — an arc of earthquake and volcanic zones that stretches around the Pacific Rim and where about 90 per cent of the world's quakes occur.

The U.S. Geological Survey said Wednesday's quake struck 81 kilometres west of Lata at a depth of 28.7 kilometres.