Venezuelan authorities promised a high-level investigation Saturday into a deadly prison riot that reportedly left dozens of people dead when National Guard soldiers clashed with armed inmates.

Vice-President Nicolas Maduro called the violence tragic while speaking on television early Saturday and said Prosecutor General Luisa Ortega Diaz and National Assembly President Diosdado Cabello would lead the investigation. He and other officials didn't give a death toll from the riot Friday at Uribana prison in the central Venezuelan city of Barquisimeto.

"The prisons have to be governed by law," Maduro said.

Ruy Medina is director of Central Hospital in the city of Barquisimeto. Medina told The Associated Press on Saturday that the number of dead from the riot at Uribana prison had risen to 61.

He told other news media initially on Friday that about 50 were killed. He said nearly all of the injuries were from gunshots. Medina said that of the 120 who were wounded, 45 of them remained hospitalized.

Relatives wept outside the prison during the violence, and cried at the morgue Saturday as they waited to identify bodies.

Penitentiary Service Minister Iris Varela said Friday that the riot broke out when groups of inmates attacked National Guard troops who were attempting to carry out an inspection.

Varela said the violence had affected a number of prisoners and officials, but said the authorities would hold off until control had been re-established at the prison to confirm the toll. She said the government decided to send troops to search the prison after receiving reports of clashes between groups of inmates during the past two days.

The death toll provided by Medina rose late Friday after he had initially reported four killed and dozens injured. Ultimas Noticias reported that the victims included a Protestant pastor and a member of the National Guard, as well as inmates.

Opposition leader Henrique Capriles condemned the government's handling of the country's overcrowded and violent prisons.

'How many more deaths do there have to be in the prisons for the government to acknowledge its failure to make changes?'—Opposition leader Henrique Capriles

"Our country's prisons are an example of the incapacity of this government and its leaders. They never solved the problem," Capriles said on his Twitter account. "How many more deaths do there have to be in the prisons for the government to acknowledge its failure and make changes?"

The Venezuelan Prisons Observatory said in a statement that in 2007 the Costa Rica-based Inter-American Court of Human Rights had ordered the government to seize weapons that inmates had in their possession at Uribana prison and to take measures to avoid deaths in the facility. The group called for the government to release a list with the names of the dead and wounded in Friday's violence, as well as details about weapons seized in the search.

"No one doubts that inspections are necessary procedures to guarantee prison conditions in line with international standards, but they can't be carried out with the warlike attitude as (authorities) have done it," said Humberto Prado, an activist who leads the watchdog group Venezuelan Prisons Observatory. "It's clear that the inspection wasn't co-ordinated or put into practice as it should have been. It was evidently a disproportionate use of force."

Prado's group says Uribana prison was built to hold up to 850 inmates but currently has about 1,400.

It was the latest in a series of bloody riots in the country's severely overcrowded prisons where inmates often freely obtain weapons and drugs with the help of corrupt guards. Venezuela currently has 33 prisons built to hold about 12,000 inmates, but officials have said the prisons' population is about 47,000.

In April and May, a prison uprising in La Planta prison in Caracas blocked authorities from going inside for nearly three weeks. One prisoner was killed and five people were wounded, including two National Guard soldiers and three inmates.

Two months later, another riot broke out at a prison in Merida, and the Venezuelan Prisons Observatory reported 30 killed.

In August, 25 people were killed and 43 wounded when two groups of inmates fought a gunbattle inside Yare I prison south of Caracas.

Chavez's government has previous pledged improvements to the prison system, but opponents and activists say the government hasn't made progress.

Varela, the prisons minister, said news media including Globovision and a local newspaper had done reports on the inspections, which she said had in fact been a "trigger for the violence."

Prado denied that, saying: "The problem isn't the work of the media. The problem is that the government hasn't disarmed the prison population."