A Syrian human rights group told Reuters that at least 62 people have been killed across Syria on Friday — including 15 villagers who tried to approach the besieged southern city of Daraa.

Thousands of people took to the streets across the country Friday, calling for President Bashar Assad's downfall and pledging support for the citizens of Daraa.

Daraa is at the heart of the country's six-week uprising. The regime has unleashed the army, backed by tanks and snipers, to crush the protest movement.

A witness in Latakia said about 1,000 people turned out for an anti-government rally when plainclothes security agents with automatic rifles opened fire. He said he saw at least five people wounded. Like many witnesses contacted by The Associated Press, he asked that his name not be used for fear of reprisal.

Other demonstrations were reported in Banias and in the northeastern city of Qamishli. The government had warned against holding any demonstrations Friday. Syrian state television said the Interior Ministry has not approved any "march, demonstration or sit-in" and that such rallies seek only to harm Syria's security and stability.

A devastating picture was emerging from Daraa, which is largely sealed off, without electricity and telephones, as residents flee to neighboring countries.

At the Jordanian side of the Syrian border, several Daraa residents who had just crossed over said there is blood on the streets of the city.

"Gunfire is heard across the city all the time," one man said, asking that his name not be used for fear of retribution. "People are getting killed in the streets by snipers if they leave their homes."

An AP reporter at the border heard gunfire and saw smoke rising from different areas just across the frontier. Residents said the gunfire has been constant for three weeks.

Since the uprising in Syria began in mid-March, inspired by revolts across the Arab world, more than 450 people have been killed nationwide, activists say.

The Muslim Brotherhood urged Syrians to demonstrate Friday against Assad in the first time the outlawed group has openly encouraged the protests in Syria. The Brotherhood was crushed by Assad's father, Hafez, after staging an uprising against his regime in 1982.