Italian doctor heightens interest in MS cause
Last Updated: Monday, February 8, 2010 | 6:31 PM ET
CBC News
Related
Internal Links
External Links
(Note: CBC does not endorse and is not responsible for the content of external sites - links will open in new window)
This scan shows blood flowing through veins in the neck of a patient with multiple sclerosis. (CBC)The Italian doctor whose unconventional thinking on the cause of multiple sclerosis is in North America to drum up interest in testing the idea.
Most MS specialists believe the condition is an autoimmune disease caused by immune cells attacking neurons in the brain and spinal cord, leading to inflammation and damage such as paralysis.
But Prof. Paolo Zamboni's idea is that a narrowing of veins in the neck interferes with blood draining from the brain, allowing iron from the blood to build up in the brain and cause a condition known as chronic cerebrospinal venous insufficiency (CCSVI).
Asked about skepticism in the medical community, Zamboni, a professor of medicine at the University of Ferrara, told reporters in Hamilton Monday: "My suggestion is to investigate patients as soon as we can, not to simply criticize. Look and confirm the data."
Zamboni was in Hamilton for two days of meetings. On Sunday, researchers from Jordan, Poland and Buffalo presented their preliminiary findings, which were not released publicly, on using magnetic resonance imaging to look for vein blockages.
Zamboni believes CCSVI is one of the causative factors in MS, not the only cause. Researchers don't know if CCSVI happens just in MS patients, he noted.
To find out more, a team at St. Joseph's Healthcare in Hamilton, Ont., hopes to recruit 200 people for a controlled study — 100 with MS and another 100 healthy people. Investigators will also focus on different types of MS, searching for any differences that patients may have in their blocked veins.
There is a debate within the medical community in Canada about whether there is enough evidence to try using surgery to open up the blockages in patients with MS.
"What the techniques would be have got to be defined yet, so this is early days to understand the association of this very interesting observation of Dr. Zamboni," said Dr. David Higgins, president of St. Joseph's Healthcare.
Tuesday is the deadline for researchers who want to apply for funding from the Multiple Sclerosis Society of Canada. The society will make $100,000 available for each of two years, and will decide which proposals to fund in a few months. The other known applicant is the University of British Columbia.
Share Tools
Top News Headlines
- Markets gain after Greece approves austerity plan
- World stock markets rise after Greece's parliament approves a new set of austerity measures that were required by international lenders in exchange for an emergency bailout. more »
- Quebec town 'heartbroken' after killing of woman, sisters
- A small Quebec town is in mourning Sunday after a Quebec man was charged with killing his nieces and his mother, who were found dead in their family home. more »
- Hit and run victim's family fears accused will walk
- The family of a young mother killed in a hit and run is outraged that the case against the alleged driver is among thousands in B.C. at risk of being thrown out because of a huge court backlog. more »
- Neil Macdonald: The death penalty debate America isn't having
- Texas's death row archive is a troubling document, not the least for what it doesn't say about those who may be wrongfully convicted, Neil Macdonald writes. more »
Latest Health News Headlines
- Electric boost helps brain learn
- People learned better when a key part of their brains got mild zaps of electricity, a finding that may someday help Alzheimer's patients keep more of their memories. more »
- Quebec takes on bullying
- The Quebec government is introducing new measures to counter bullying in schools. more »
- Smoking pot doubles car accident risk
- Smoking marijuana a couple of hours before you drive almost doubles your chances of having a serious car crash, say Canadian researchers. more »
- Teddy bear sale raises money for charity
- The family of a Vancouver school teacher who died of cancer sells off her teddy bear collection to raise money for charity. more »
FEATURED HEALTH
- Adele wins best album, best record Grammys
- Houston autopsy results withheld by police
- Quebec town 'heartbroken' after killing of woman, sisters
- Greece passes new austerity deal amid rioting
- Pop queen Whitney Houston dies at 48
- Northern lights viewed from space
- Manitoba man dies after falling off moving SUV
- Doors blocked in fatal Manitoba trailer blaze
- Former Stanley Park petting zoo goats feared slaughtered

