Canada OKs vaccine to prevent painful shingles in seniors
Last Updated: Wednesday, August 27, 2008 | 12:54 PM ET
CBC News
Related
Internal Links
External Links
(Note: CBC does not endorse and is not responsible for the content of external sites - links will open in new window)
Health Canada has approved a vaccine to help prevent painful shingles in people 60 or older who had chickenpox earlier in life.
Zostavax, made by Merck Frosst Canada, should be available through doctors and pharmacies starting sometime next year, the company announced Tuesday.
Shingles occurs when the chickenpox virus reactivates after lying dormant in nerve cells, sometimes for decades, and starts reproducing again. In other cases, the virus may stay dormant indefinitely.
Shingles, also called herpes zoster, causes a painful red rash and sensations of tingling, itching and burning. The rash can lead to scarring and the pain can persist in some people for months or years. Up to 20 per cent of adults who have had chickenpox will get shingles later in life.
Older age, suppressed immune status and lack of re-exposure to the varicella virus seem to increase one's risk of developing shingles, said Dr. Allison McGeer, an infectious diseases specialist at Mount Sinai Hospital in Toronto.
Previously, adults may have gained a natural booster by being exposed to children infected with chickenpox. But as more young children in North America are vaccinated against chickenpox, it is theorized that fewer adults could be gaining that natural boost to their immune system that helps keep the virus dormant.
Since studies from Alberta, Manitoba and British Columbia reported increased shingles rates before chickenpox vaccine campaigns began in those provinces, there is also some evidence suggesting the incidence of shingles was on the rise before the chickenpox vaccine, said Dr. Rafael Harpaz, a herpes virus expert from the U.S. Centers for Disease Control.
Merck has not yet said how much the vaccine will sell for in Canada.
The vaccine was approved for use in the U.S. in 2006.
When the U.S. approval was announced, the company said the long-term effectiveness of the vaccine wasn't clear. Merck's research shows it works for at least four years, and the company plans to follow patients for 10 years to track the vaccine's effectiveness.
It's also not yet clear whether seniors will need more than one injection, or how well the vaccine works in people with weakened immune systems and are at greater risk of developing shingles, McGeer said.
Share Tools
Top News Headlines
- CP Rail negotiations 'stalled,' union says
- Negotiations between Canadian Pacific Railway Lt. and the union representing 4,800 striking locomotive engineers and conductors have come to a "stall" after the government appointed mediator walked out at 2 p.m. ET, a union spokesman says. more »
- Syria massacre toll up to 108, UN monitor says
- The UN Security Council is holding an emergency meeting Sunday to discuss the recent massacre in the Syrian town of Houla, in which 108 people died, many of them children under the age of 10. more »
- Ryder Hesjedal wins prestigious Giro d'Italia
- Victoria, B.C., native Ryder Hesjedal has become the first Canadian to win one of the cycling world's three Grand Tour events, wrapping up the 2012 Giro d'Italia with an excellent performance in the final stage in Milan. more »
- Neighbour may have helped find missing kids in Mexico
- Two Winnipeg children who had been missing for nearly four years were found in Mexico after a man raised concerns about his neighbour, according to a private investigator. more »
Latest Health News Headlines
- Alcohol addiction team wants higher energy drink prices
- Mixing alcohol with caffeine-rich energy beverages is a trend that is continuing to rise in Canada, despite repeated warnings that the combination is unsafe, a new report warns. more »
- How curry spice helps the immune system kill bacteria
- A spice used in curry dishes helps to prevent infection and now scientists think they've got a lead on how. more »
- Calgary EMS station opens to the public
- Curious Calgarians got a look at a northwest EMS station this morning. more »
- Yellowknife toddlers catching hand, foot and mouth virus
- An outbreak of hand, foot and mouth disease in Yellowknife is causing many toddlers and their parents some major discomfort. more »
FEATURED HEALTH
- Teen struck by lightning in Ottawa dies
- Missing Winnipeg children found in Mexico
- Quebec tornadoes cause millions in damage
- Montreal protesters march in peaceful defiance
- Syria massacre toll up to 108, UN monitor says
- Woman's remains found in hockey bag on Cape Breton river
- Everest team unable to bring down Toronto woman's body
- WWE apologizes to Brazil over Canadian's flag stomp
- Lady Gaga nixes Indonesia show after threats

