Virus linked to development of deadly skin cancer: study
Last Updated: Thursday, January 17, 2008 | 5:05 PM ET
CBC News
A newly discovered virus has been linked to the development of Merkel cell carcinoma, a dangerous skin cancer.
Researchers at the University of Pittsburgh Cancer Institute spent 10 years developing a way of isolating the virus, named Merkel cell polyomavirus (MCV).
Polyomaviruses have been linked to cancer in animal studies.
"This is the first polyomavirus to be strongly associated with a particular type of human tumour," said Dr. Moore, professor of microbiology and molecular genetics at the University of Pittsburgh School of Medicine and leader of the molecular virology program at UPCI, in a release.
"Although polyomaviruses have been studied in relation to cancer development for years, the weight of scientific evidence had been leaning toward the view that these viruses do not cause human cancers."
Merkel cell carcinoma is a fast-moving skin cancer that develops from nerve cells and quickly invades other tissues and organs in the body. This incidence of this type of cancer has increased dramatically over the 20 years and now averages 1,500 cases per year.
Those vulnerable to this form of cancer are immune-suppressed individuals — such as those taking drugs to prevent the rejection of a transplant — and AIDS patients.
The survival rate isn't high, with 50 per cent of patients succumbing to the disease within nine months.
In the study, researchers discovered that many people carry MCV, though in many it never develops into cancer.
Moore says the discovery opens the door to further exploration into how the virus targets cell pathways. "Information that we gain could possibly lead to a blood test or vaccine that improves disease management and aids in prevention," he said.
He likens the possible future treatments to the HPV vaccine that protects against certain strains of human papillomavirus, which is linked to cervical cancer.
Corrections and Clarifications
- Merkel cell polyomavirus is a newly discovered virus. It has not been linked to Kaposi's sarcoma as this story originally reported. The HPV vaccine protects against certain strains of human papillomavirus, not cervical cancer as was originally reported in this story. Jan. 18, 2008 | 12:39 p.m. ET
Share Tools
Top News Headlines
- Montreal protesters march in peaceful defiance
- The clanging of pots and pans sounded throughout Montreal's downtown core Saturday night and into early Sunday morning, as thousands of protesters marched on in peaceful — but loud — defiance of Bill 78. more »
- Quebec tornadoes cause millions in damage
- Environment Canada confirms that two tornadoes — one of which was classed as a moderate F-1 packing winds of up to 150 km/h — touched down near Montreal Friday night, causing millions of dollars in damage. more »
- Teen struck by lightning in Ottawa dies
- The victim of a Friday lightning strike during a storm in east Ottawa has died, CBC News has learned. more »
- Missing Winnipeg children found in Mexico
- Two Winnipeg children reported missing and possibly in Mexico have been found alive, according to unofficial reports from an agency that works to find missing people. more »
Latest Health News Headlines
- Alcohol addiction team wants higher energy drink prices
- Mixing alcohol with caffeine-rich energy beverages is a trend that is continuing to rise in Canada, despite repeated warnings that the combination is unsafe, a new report warns. more »
- How curry spice helps the immune system kill bacteria
- A spice used in curry dishes helps to prevent infection and now scientists think they've got a lead on how. more »
- Yellowknife toddlers catching hand, foot and mouth virus
- An outbreak of hand, foot and mouth disease in Yellowknife is causing many toddlers and their parents some major discomfort. more »
- Super microscope installed at University of Victoria
- What's heralded as the world's biggest microscope has arrived at the Unversity of Victoria, marking the culmination of a 10-year effort by one of the school's professors. more »
FEATURED HEALTH
- Teen struck by lightning in Ottawa dies
- Missing Winnipeg children found in Mexico
- Quebec tornadoes cause millions in damage
- Woman's remains found in hockey bag on Cape Breton river
- Pope's butler arrested in Vatican leaks scandal
- Montreal protesters march in peaceful defiance
- Everest team unable to bring down Toronto woman's body
- What a Greek euro exit could mean for Canada
- WWE apologizes to Brazil over Canadian's flag stomp

