James Cotton, a Grammy Award-winning blues harmonica master whose full-throated sound backed such blues legends as Muddy Waters, Sonny Boy Williamson II and Howlin' Wolf, has died at age 81.

A statement from Alligator Records, Cotton's label, says he died Thursday of pneumonia at St. David's Medical Center in Austin.

The Mississippi Delta native performed professionally since age nine. Cotton backed Muddy Waters in his landmark album At Newport on Chess Records.

Rock and Roll Hall of Fame Show

Ben Harper, left, and James Cotton perform at a Rock and Roll Hall of Fame event in New York on March 10, 2008. (Jason DeCrow/The Associated Press)

After going solo in the 1960s, Cotton released almost 30 albums, including his 1996 Grammy Award-winning Verve album, Deep In The Blues. His most recent album, Cotton Mouth Man for Alligator Records in 2013, was nominated for a Grammy.

Cotton spent considerable time touring in Canada and recorded or jammed with the likes of Ronnie Hawkins, Colin Linden and Downchild Blues Band.