Pitt and Chatham Streets between Bruce and Church Avenues will be closed permanently starting next Tuesday, as construction gets underway on Windsor's new Family Aquatic Centre.
The area will eventually become part of the footprint of the city's new 50-metre pool.
Project Manager Don Sadler said initial preparation of the parking lot is complete.
"We did a lot of hydro re-locates and abandoned some of the utility services and we wanted to give the parkers enough time to find other locations," Sadler told CBC News.
Sadler expected the official groundbreaking on the $77-million project to happen sometime in March, with the goal for completion being the International Children's Games in the summer of 2013.