The Canada Border Services Agency announced on Thursday that it seized 53 kg of cocaine and 22 kg of methamphetamine at the Ambassador Bridge earlier this month.
The CBSA said it made the seizure on Aug. 4.
Officials said a commercial truck was sent to secondary inspection upon returning to Canada. Agents examined the tractor-trailer and found what what they called "inconsistencies" in the front wall of the cargo trailer.
After removing interior panels of the trailer, agents found a number of packages of cocaine and methamphetamine.
The 61-year-old truck driver, a man from Colborne, about 140 kilometres east of Toronto, is charged with two counts each of importing a controlled substance and possession for the purposes of trafficking.
He's out of custody and has a September 9th court appearance in Windsor.
This is the second significant drug seizure for the CBSA at the Ambassador Bridge in the past four months. On May 28, CBSA officers seized 22 kg of cocaine.