A 48-year-old Mississauga man died this weekend after his motorcycle struck the back of a pickup truck on Highway 401.

The crash in the eastbound lanes of the highway, near Highway 427, at 1:29 p.m. Saturday.

While the driver of the motorcycle was killed in the crash, a 14-year-old male passenger was airlifted to hospital with serious, but non-life threatening injuries.

The two people inside the pickup truck were not hurt.

The crash remains under investigation.