A man was taken to hospital following a multi-vehicle crash on Highway 401 near Keele Street overnight.

At around 12:30 a.m. Friday a broken down vehicle was being assisted by a tow truck when a third vehicle hit them from behind, pinning the motorist between the two vehicles.

One man was taken to hospital with life-threatening injuries and another with minor injuries.

Collectors lanes were closed until after 5 a.m.