One pedestrian is dead and two other people were rushed to a trauma centre after a car careened onto the sidewalk at Yonge Street and Empress Avenue on Thursday afternoon.

EMS confirmed one person was pronounced dead at the scene. A witness told CBC News he believed the victim was male.

The collision happened around 1:20 p.m. when a female driver lost control of her grey sedan.

Pedestrians were struck by a car on Thursday afternoon at Yonge and Empress.

Emergency crews raced to get four patients to hospital following the crash. One person was pronounced dead at the scene. (Mike Wise/CBC)

Witness Crystal Robbescheuten said the female driver was eastbound on Park Home Avenue, which turns into Empress Avenue east of Yonge, when she struck a cab near the intersection. The driver then lost control and seemed to accelerate north on Yonge Street where she plowed into a concrete planter and then struck the pedestrians, Robbescheuten said.

The sedan, which was badly damaged in the collision, came to rest in a parking lot where it collided with a Porsche SUV.

Several people in the area raced to provide first aid before paramedics made it to the scene.

EMS officials say they transported four patients in total, two of whom had serious injuries and were taken to a nearby trauma centre and two others who suffered moderate injuries.

It's believed the driver was one of those taken to hospital, though the extent of her injuries are unknown.

Yonge Street has been closed from Empress Avenue to Elmwood Road as police investigate.