Sudbury police are investigating the first murder of 2014 in the Donovan neighbourhood.
Police were called to the the area of Bloor and Kathleen Streets on Tuesday afternoon after a report of a stabbing.
A 20-year-old man was located who had been stabbed with an edged weapon.
He was taken to hospital and died as a result.
Police say the victim has been identified as Allen Ashawasagai of Sudbury.
A 17-year-old girl has been charged with second degree murder and possession of a weapon for a dangerous purpose. She will remain in custody until a court appearance on June 12.
Police say this was not a random incident.
"We wanted to reassure the public that this wasn't a random act, that the individuals involved knew each other and that we are confident that there are no further public safety concerns,” said Sudbury police Inspt. Rob Thirkill.