A chaotic scene unfolded in a Saskatoon neighbourhood, where a man on foot was chased down and hit by a woman in a car, police say.

The bizarre incident took place on the 500 block of Avenue M, near E.D. Feehan High School.

According to police and an eyewitness, a young man was seen running down the street shortly after 1 p.m. CST, trying to evade two women in a car.

Police said there had been some sort of an altercation on the front lawn of a home in the area that seemed to set things off.

"The 25-year-old man involved walked away from the altercation heading south," police said. "The females involved, 29 and 27 years old, followed him a short distance ... in a car to an alley."

Police said the man was struck by the car and then run over, resulting in serious injury.

Justis Adkens, who lives in the area, told CBC News he saw things unfolding in a dangerous way and called police.

By the time he got off the phone and went back outside, the man had been hit by the car.

"There was a crowd there already," Adkens said. "He was quite bloody and quite hurt. And one of the ladies grabbed him and drug him into the car and threw him in the back seat.  And then the other one jumped into the driver's seat."

Adkens said the car did not get far.

The vehicle jumped over a curb, hit a tree and then smashed into the front of a house. No one was hurt in the crash.

That's when police and an ambulance arrived.

The injured man was taken to hospital.

Police said a 29-year-old woman, the driver of the car, is facing charges, including impaired driving causing injury.

The other woman who was involved was originally detained but has since been released with no charges.

Police said the man's injuries were serious, but not life-threatening.