The Syrian embassy in Ottawa was vandalized overnight when the front of the building was splashed with red paint.
The vandalism coincided with weekend protests asking the international community, including Canada, to intervene to end the violence in the country.
About 40 people demonstrated outside the embassy on Saturday to denounce the regime of leader Bashar Assad, and Friday evening Canadians of Syrian descent held a candlelight vigil.
"Lots of people spent their blood to give us the freedom we are living [in Canada]," Syrian-Canadian Farid Hadded told CBC News at the vigil.
"Now, at this time, lots of people back home in Syria are also paying the price for our kids' future to live in democracy and freedom."
It's not clear if people at either protest were involved in the vandalism. RCMP are investigating.
The embassies of Syria in six other countries have also been vandalized.
The embassy in Cairo was burned and various furniture were destroyed, while the embassy in London had its windows broken.