Ottawa paramedics say three people were injured, including one seriously, after a crash in the city's south end Friday evening.

Emergency crews responded to the intersection of Spratt and Earl Armstrong roads, which is in the Riverside South neighbourhood, at about 6:10 p.m. for a two-vehicle head-on crash.

There was significant damage to both vehicles, paramedics said.

Fire officials said two off-duty police officers and a nurse on her way to work assessed four people before crews arrived.

Firefighters then removed the driver's door of one vehicle and extricated the female driver, who was the only person inside. There were three people inside the other vehicle.

Paramedics said they treated a 49-year-old woman for head injuries and she was taken to hospital in serious but stable condition.

A 30-year-old woman was also taken to hospital in stable condition suffering a fractured wrist and some scrapes and a 39-year-old man was taken to hospital with scrapes.

A seven-month-old boy was also in a car seat but he was not injured.

Ottawa police are investigating.