The Salt River First Nation is separating from the Akaitcho First Nation.
Chief Dave Poitras said the Salt River First Nation needs to move on in order to make economic headway.
The First Nation has settled its treaty land entitlement but Poitras says the Akaitcho First Nation is nowhere near finalizing their claim.
"Being part of them left us with no voice," Poitras said.
"We’re parting because we need to do this for our nation. We need to have a voice and we can no longer wait for Akaitcho to negotiate their claim because they’re always so afraid of jeopardizing their claim," he added.
Poitras said the group leaves with no animosity toward other First Nations.
The group has filed the required six month notice to the Yellowknives Dene First Nation, the Lutselk'e Dene First Nation and the Deninu Kue First Nation in Fort Resolution.
It has also submitted letters to the territorial and federal governments requesting to be included in future discussions, such as amendments to the Wildlife Act and devolution talks.