The formal application to have Mistaken Point declared a World Heritage Site has been delivered to UNESCO in Paris.
The area near Cape Race on the southern Avalon is home to some of the oldest fossils on Earth.
Hundreds of tourists flock to the site each year to marvel at evidence of the world's earliest lifeforms.
A team of experts will visit the site this summer as part of the evaluation process, with a decision expected in 2016.
The province has spent almost $650,000 on the Mistaken Point application.
If successful, it would be the fourth World Heritage Site in the province.
The others are Red Bay, Labrador, Gros Morne National Park, and the Viking settlement at L'anse aux Meadows.