The Clarenville campus of Keyin College will close in December because of a steep decline in enrolment.
President Des Whalen said there are now just nine students at the campus, and the college is no longer accepting students.
"I think the the demographics are a key issue here. The economy is not helping as well as the economy has slowed a little bit. And it's up to us to be reasonable and to be proactive," said Whalen, who blames a slowing economy and stagnant population growth for the decision to close.
The closure will impact three jobs at the campus. Whalen said they have either found news jobs or accepted positions at one of the other Keyin College campuses throughout the province.
The campus focused on business, technology training and occupational health and safety programs.
A couple of years ago, enrolment reached a peak of 50 to 60 students.
Whalen said the decline is being noticed at other campuses as well.
Keyin College has operated in Newfoundland and Labrador for more than three decades.
According to its website, Keyin also has operations in Burin, Carbonear, Fortune, Grand Falls-Windsor, Lewisporte, Marystown, Port aux Basques, Springdale, St. John's, St. Lawrence and Stephenville.