The federal government is planning to close its DFO office in Grand Bank at the end of the month, centralizing its operations in Marystown.
But Grand Bank Mayor Rex Matthews said the town remains a hub in the fishing industry, while Marystown no longer has a plant.
"I mean the fishery's still here, it's still going strong, both in the offshore and the inshore — so here is where they should be to," said Matthews.
"Here's where the fishermen were to, here's where the processing facilities were to, so you would think that DFO would want to stay in a community where you have all the activity. This type of a decision-making process is not acceptable."
Grand Bank has lost other federal government offices.
Matthews said unless residents take a stand, the trend will continue.
"Our community has to support this, because they'll close this office one day, the next day it will be some other office going."
Matthews said if the decision isn't reversed, he will step up his campaign and organize a protest in front of the DFO office next week.
Federal officials have said selling the Grand Bank building will cut costs without cutting jobs.