A blizzard warning has been issued by Environment Canada for the Avalon and the southern coast of Newfoundland for Tuesday.
Snow and blowing snow conditions are expected to develop overnight Monday, with strong northeasterly winds.
Conditions will continue into Tuesday as the low pressure system approaches the Avalon area.
Rodney Barney, meteorologist with the Gander weather office, said the heaviest snow will likely fall Tuesday morning around rush hour.
"Expecting generally 20 to 30 centimetres of snow across the Avalon Peninsula with winds gusting as high as 90 km/h, especially during the morning hours," Barney told CBC's St. John's Morning Show.
"So I would think that during the morning rush hour tomorrow it's going to be quite dirty in fact with that snow and wind."
However, Environment Canada says it's uncertain whether the system will pass over the peninsula or just the southeast portion.
Forecasted snowfall amounts across the Avalon will range between 20 and 30 centimetres, with a possibility of switching to rain or freezing rain with temperatures expected above 0°C Tuesday afternoon.
In addition, winds are expected to gust as high as 90 km/h to create blizzard conditions with near zero visibility, Environment Canada warns.
"It will be looking a lot more like winter compared to what's been seen over the last week or so," said Barney.
Marine Atlantic has cancelled Monday crossings between Port aux Basques and North Sydney because the weather is expected to be poor.
'It will be looking a lot more like winter compared to what's been seen over the last week.' - Rodney Barney
The 11:45 a.m. crossing from Nova Scotia was cancelled, as well as the 11:45 p.m. crossings in both directions.
Meanwhile, snowfall in the Clarenville and Terra Nova areas and along the coast from Port aux Basques through to the Burin Peninsula is expected between 15 and 25 cm by late Tuesday, with strong northeasterly winds.
Gusts are expected to reach 90 km/h, but locally will gust up to 120 km/h along the south coast of the island.
Southern parts of the island can expect improved conditions late Tuesday afternoon, and elsewhere conditions should improve by Tuesday evening.
Those conditions are scheduled to improve late Tuesday, as the system moves away.
No rest for the west
Corner Brook will only see about two to four centimetres of snow Tuesday, but that comes on top of a weekend winter wallop that weather blogger Kyle Brookings estimates dropped up to 35 centimetres from Friday through to Sunday.
"It seems like an average winter so far, and last winter at this time, we had more snow than we what have right now, so we can't really complain about that," said Brookings.
"It wouldn't be winter on the west coast if we weren't getting all these storms move through."
And west coasters won't have to wait long to fire up those snowblowers again.
Special weather statement for 2nd system
Bay St. George up to the Northern Peninsula sits under a special weather statement for potential messy weather starting Tuesday night.
Meanwhile in central, Environment Canada warns of a winter storm watch in Grand Falls-Windsor, Gander and Buchans and the interior.
As of 4 p.m. Monday, Environment Canada said current snowfall amounts are likely to reach 15 to 25 cm by late Tuesday, with blustery conditions continuing through Tuesday night.
A special weather statement has also been issued for the entire island for Wednesday, as a second low system is forecast to quickly follow behind the first.
Environment Canada said the track of the second system is still uncertain, but it will likely be headed for west of the Avalon Peninsula.
The current forecast will likely mean some snow passing through the Avalon areas late Tuesday night into early Wednesday, but Barney said that should quickly change to rain.
That switch to rain is expected to happen later on the Burin Peninsula and the surrounding area, Barney added.
Neither of the two systems are expected to reach Labrador.