Firefighters from several departments battled flames for almost four hours at a house fire in St. John's on Saturday night.

Three firefighters were taken to hospital after battling the stubborn blaze on Goodridge Street. 

Deputy Fire Chief Don Byrne said the fire started around 6p.m. in the basement of the two story home, but quickly shot up through the floor and into the attic space.

No one was home at the time.

Byrne said firefighters were called out of the home when the floors caught fire, because it became too dangerous to fight the flames from inside.

All three firefighters who went to hospital were likely suffering from heat exhaustion.

"These were the guys who were into the basement or upstairs," Byrne said.

"The temperatures here got so warm all of a sudden this evening, that coupled with the heat inside."

The firefighters were taken to hospital as a precaution.

Byrne said that it is always an anxious time when colleagues require medical attention.

"They're in there getting checked out to ensure everyone is good," said Byrne. "(We're) always worried until they say that everything is fine."

Byrne said it appeared that the house was undergoing renovation, but the cause of the fire is still unknown.

The Royal Newfoundland Constabulary is investigating the incident.