Moncton fire investigators and police dog services are at the scene of a downtown house fire, trying to determine the cause.
It took firefighters about three hours to extinguish the blaze at 32 Waterloo St.
Crews remained on the scene into the afternoon, pouring water on "warm spots," said Platoon Chief Rob Brine.
No one was injured, but the two-storey home sustained significant damage.
The roof and back half of the building were destroyed.
Officials say the house will likely have to be torn down.
The fire started at about 8:40 a.m.
Neighbours say two tenants who lived in one of the building's apartments were evicted on Thursday night.
Off-duty Deputy Fire Chief Don McCabe noticed the blaze and called it in.
Within minutes, three fire trucks were on site, battling the fire, which was concentrated on the top two levels.
Although it was initially unclear whether anyone was inside when the fire broke out, officials have now confirmed the building was empty.
Fire Chief Eric Arsenault had said he was hopeful nobody was in the home.
"No one answered the cry, so that's a good sign, but we'll only be able to confirm that once we put firefighters in the building and do a proper search."
Nobody could have survived the fire, Arsenault had said.
Waterloo Street was closed while firefighters battled the blaze and traffic on Assumption Boulevard was slow.