Fire crews were called to a Winnipeg home Tuesday night. (CBC)The four-month-old Winnipeg girl who was hospitalized following a devastating fire that killed her mother, grandmother and two sisters has died, according to Shahina Siddiqui, executive director of the Islamic Social Services Association.

Hoorya Farooq was rescued from a burning house in Winnipeg's West Kildonan neighbourhood on Tuesday night. She was the only survivor of the blaze.

Hamid Farooq, the girl's father, is a shift worker and was not home at the time of the fire.

Farooq's wife Zebunesa Sadiq, 33, his mother Shemeem Akhtar, 60, and his daughters Fayza Peyawary, nine, and Aliza Sadiq, four, all died in the heavy smoke and fire that spread through their semi-detached home on Woodlark Place.

The infant was on life support in hospital and, according to a relative, there had been no brain activity since the fire.

On Friday, the father who spent the past few days at his daughter's bedside, made the difficult decision to take the girl off life support.

She died at 5:30 p.m., almost immediately after her life support was turned off, Siddiqui said.