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Guelph Police have arrested a man and a woman following an investigation into crystal methamphetamine and heroin trafficking in the east end of the city. (Guelph Police Service)

A 44-year-old man and a 43-year-old woman in Guelph have been charged with a number of offences after police seized cash, drugs and a weapon from a home near the city's hospital.

Earlier this month, police started an investigation into crystal meth and heroin trafficking in the east end of the city. Officers executed a search warrant at a home on Sunnylea Cres., and seized cash, heroin, meth, oxycodone, marijuana, a replica handgun and a prohibited weapon.

The man and woman have been charged with two counts of possession of a controlled substance for the purpose of trafficking, four counts of possession of a controlled substance, and unauthorized possession of a weapon.

The woman also faces a charge of possession of a firearm or weapon contrary to a prohibition order.

The man has also been charged with two counts of possession of a firearm or weapon contrary to a prohibition order, three counts of breach of probation and two counts of breach of recognizance.