'Significant' factory fire in Cambridge closes Sheffield Street

Fire crews are on scene at a blaze at a factory in Cambridge. Police have closed Sheffield Street and some buildings in the area have been evacuated.

Large amount of smoke pouring from factory on Sheffield Street

The city is warning residents to stay away from a fire at a factory on Sheffield Street in Cambridge. (@cityofcambridge/Twitter)

Fire crews are battling a "significant" blaze at a factory on Sheffield Street in Cambridge.

The fire broke out Monday afternoon at 105 Sheffield Street, the location of Vandem Industries. Police have closed the road and some buildings on the street have been evacuated as a precaution.

Grand River Transit said bus routes 51 and 203 have been diverted, and city officials are telling residents to avoid the area.

"Asking residents and schools to shelter in place. Keep doors and windows closed," the Cambridge Fire Department tweeted. "Fire crews at significant fire event in Hespeler."