Two good friends were likely on their way home from target shooting on Saturday evening when the car they were driving crossed a centre lane and slammed into a truck, killing them both.

Around 6:45 p.m. Saturday, the OPP say, a Honda Accord going northbound on Highway 6 near Chippewa Road crossed the centre line and struck an oncoming pickup truck.

Unable to swerve out of the way, a Chevy Cruz crashed into the rear of the pickup and became wedged underneath the bed of the truck.

The two occupants of the Honda — David Anderson, 64, and Dulce Bustria, 53, both of Hamilton — were pronounced dead at the scene.

Anderson’s brother Don told CBC Hamilton his brother was “very much a sportsman, an outdoorsman and also a collector.” He made his living as a dental technician.

“He had great interest in sports, loved to fish — that was one of his big passions — and boating,” Anderson said.

Don said his brother was likely returning home from an afternoon of target shooting with his “good friend” Bustria.

Paramedics transported three other victims to hospital, two in “serious” condition and one with “non-life-threatening injuries,” said Marc Tremblay, a spokesperson with the Hamilton Paramedic Service.

In a statement released Sunday afternoon, the OPP said it's not known why the Honda crossed into oncoming traffic.

Sgt. Dave Woodford, of the OPP’s highway safety division, said earlier in the day that he doesn’t believe alcohol and speed were factors in the fatal collision, but noted the investigation is ongoing.

“We have no idea why the vehicle veered into the opposite lane,” said Don, who added it is highly unlikely his brother was driving under the influence of alcohol.

Anderson had two children, Davina Dell and Kevin Anderson.

The coroner is investigating and will perform an autopsy in the coming days, Woodford says.

Police ask anyone with information on the crash to call the OPP’s Burlington detachment at 905-681-2511.