Calgary police and the RCMP seized nearly $1 million worth of illegal drugs and a fully automatic AK-47 assault rifle in a bust earlier this week.
The raids on Monday came after a six-month investigation focusing on several suspects who had recently relocated from Vancouver's lower mainland, police said.
Investigators believe the suspects were trying to gain a foothold in Calgary's drug market.
"The supply of drugs coming into this province is substantial. We know the economy is good and there is a market for illegal drugs unfortunately," said Insp. Gerry Francois of the Alberta Law Enforcement Response Teams (ALERT).
Acting on four search warrants, officers discovered a stash of drugs, weapons and cash as well as a full-scale cocaine conversion lab.
About 115 kilograms of "superbuff" — an agent used to cut or dilute the purity of cocaine in order to maximize profits — was also found, along with significant quantities of marijuana, MDMA and methamphetamine.
Three men in their 20s face 64 drug and weapons related charges. More charges are pending, police said.
The 400-member ALERT team is made up of municipal police, RCMP and provincial sheriffs.