A woman was killed and a man was seriously injured in a shooting at a North Burnaby apartment building Tuesday night. (CBC)

Two people are dead, two others wounded and a home is riddled with bullet holes following a wave of shooting incidents in Metro Vancouver Tuesday night.

A woman was killed and a man was seriously wounded in the first incident, a shooting in the 25th-floor penthouse of a luxury high-rise at 2345 Madison Ave. in Burnaby, shortly after 8 p.m. PT.

Corp. Dale Carr of the regional Integrated Homicide Investigation Team said it was too early to say what the motive may have been or whether the shooting may have been gang-related.

"I wouldn't want to start to speculate it being linked to gangs or drugs …This may be a domestic homicide. We don't know," Carr said.

Targeted hit in East Vancouver

In the second fatal shooting of the night, Vancouver police found a man in his 20s slumped over the steering wheel of his car in East Vancouver.

Police say a fatal shooting Tuesday night in East Vancouver appears to have been a targeted hit. (CBC)

He had been killed in what appeared to be a targeted hit sometime after 9 p.m. at East 3rd Avenue and Kaslo Street, according to Vancouver police Insp. Bob Chapman.

"Blood on his face, shell casings on the ground — right now we're investigating a homicide. It has all the earmarks of another gangland-style hit," Chapman said.

Witnesses saw two suspects in dark clothing running from the scene, police said.

2 Surrey shootings

Surrey RCMP also handled two shooting incidents on Tuesday evening, but neither resulted in fatalities.

In one incident, police investigated reports of shots being fired around the 68th Avenue and 130th Street at about 8 p.m. A short time later a man in his 20s arrived at a nearby hospital with gunshot wounds, RCMP Staff Sgt. Geoff Shaw told CBC News.

In the other incident ,someone in a vehicle fired shots at a house near 110th Avenue and 155th Street. There were no reports of injuries, but Mounties said the home was well known to them.

The shooting followed the arrest of several people over the weekend with links to the Lower Mainland's notorious UN gang, which police allege is engaged in a violent turf war with rival gangs for control of the region's illegal drug trade.