Long-time CNBC business anchor Mark Haines has died suddenly at the age of 65, the network announced Wednesday.

In a statement, CNBC said Haines died at home Tuesday night. It gave no further details. 

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Mark Haines was a familiar face on U.S. business channel CNBC. He suddenly died Tuesday at the age of 65. (CNBC)

Haines was a 22-year veteran of the business news channel, founding CNBC's morning show Squawk Box. He was also co-anchor of the network's Squawk on the Street program.

"With his searing wit, profound insight and piercing interview style, he was a constant and trusted presence in business news for more than 20 years," CNBC president Mark Hoffman said in a statement to CNBC employees. "From the dotcom bubble to the tragic events of 9/11 to the depths of the financial crisis, Mark was always the unflappable pro."

Barry Ritholtz, head of the research firm Fusion IQ, said Haines was "a no-nonsense straight shooter" who was notably skeptical during the 1990s when other business anchors were busy cheering what turned out to be a stock market bubble.

"He was trained as an attorney," Ritholtz said. "He brought that keen lawyer's eye to everything he did. It wasn't something often seen in the financial media."

During the depths of the last financial downturn, Haines famously called a bottom to the U.S. stock market decline on March 10, 2009. He ended up being off by just one day.  

Haines was such a well-known fixture on Wall Street that when news of his death spread through the floor of the NYSE Wednesday morning, traders paused for a minute of silence. 

He was on air as recently as last Friday. Less than three weeks ago, Haines bid a teary goodbye to fellow anchor Erin Burnett, who quit CNBC for a job at CNN.

He leaves a wife and two children.

With files from The Associated Press