The White Stripes announced Wednesday they are splitting up after more than a decade making music.
Jack and Meg White posted the news on their website, saying they would make no further recordings or live performances.
"The reason is not due to artistic differences or lack of wanting to continue, nor any health issues as both Meg and Jack are feeling fine and in good health," the post read.
"It is for a myriad of reasons, but mostly to preserve what is beautiful and special about the band and have it stay that way."
The groundbreaking rock duo are credited with helping revive and reshape a stale rock scene with their scorching, blues-tinged songs.
One of their last recordings was Under the Great White Northern Lights, a live album from their tour of Canada in 2007. The tour also became a documentary of the same name.
Jack White was songwriter, vocalist and guitar player and Meg White, his ex-wife, played drums in the band, which started off in Detroit in 1997.
They became big with the release of White Blood Cells in 2001 and Elephant in 2003. Their last three albums each won the Grammy Award for best alternative album.
Over the years, Jack White has become involved with other projects, including the bands the Dead Weather and the Raconteurs. He is also a producer behind Third Man Records and has worked with artists such as Loretta Lynn and Wanda Jackson
Third Man Records will continue to put out unreleased live and studio recordings from The White Stripes, the post said.
The post thanked fans for their support.
"The White Stripes do not belong to Meg and Jack anymore. The White Stripes belong to you now and you can do with it whatever you want," their statement said. "The beauty of art and music is that it can last forever if people want it to. Thank you for sharing this experience."