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Spider-Man: Turn Off the Dark, in previews at Manhattan's Foxwoods Theatre, had its fourth accident on Dec. 20 when a stuntman fell close to the end of the evening's preview show. ((Kathy Willens/Associated Press))

The bleeding continues on Broadway's Spider-Man musical with an exit by one of the play's lead performers, Natalie Mendoza.

Mendoza, who sustained a concussion on the injury-plagued production in November, has reportedly left Spider-Man: Turn Off the Dark, according to the New York Times.

The article quotes two sources working on the play, who have asked to remain anonymous because the show's producers have forbidden public comments as they hammer out an agreement concerning the actress's departure.

The report comes just days after the musical's lead actor, Reeve Carney, proclaimed it was "a safer show."

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Natalie Mendoza worked closely with director Julie Taymor on the villainess Arachne, who also sings the play's title song. ((Spider-Man: Turn Off the Dark) )

Mendoza portrays the key role of Arachne, a major source of Peter Parker's transformation into Spider-Man.

A series of accidents, four in total, has forced the producers to delay the play's official opening by four weeks until Feb. 7. The show is currently in previews.

Mendoza was hit in the head by a rope holding a piece of equipment during a show on Nov. 28.  She was off stage at the time.

She had been advised by a specialist to take time off the production to recover but insisted on performing three days later. By the end of the show, the 30-year-old actress  was suffering from a headache and nausea.

Mendoza decided to stay off the stage for two weeks.

In a Sunday posting on her Facebook page, the Australian-British actress said she was down to four painkillers and two nausea pills a day: "Nice to be almost back to normal."

Then, in a post on Twitter, Mendoza wrote: "Can feel a trip to India coming on."

No one with the production will comment on the report of Mendoza's departure.

Actor in hospital after tumble

The play has been hampered with a series of accidents since September when the production was still in rehearsals.

First a dancer broke his wrists during a flying stunt. Then another actor injured his feet performing the same move.

On Dec. 20, Christopher Tierney was severely injured after plunging from a ledge into the stage pit while performing as Spider-Man. Tierney remains in a New York city hospital with four broken ribs, fractured vertebrae, a broken scapula, a bruised lung and a hairline fracture on his skull.

That day also marked Mendoza's last appearance on stage as her understudy, America Olivo, filled in as Arachne from then on.

According to the Times article, Mendoza's exit would be a huge blow to the musical as she had worked closely with director Julie Taymor on the character. Much of the plot in Act 2 revolves around Arachne, who also sings the production's title song.

The $65-million show, considered the most expensive ever mounted on Broadway, contains music and lyrics by U2's Bono and the Edge.