British actor Bob Hoskins says he is retiring after being diagnosed with Parkinson's disease.
In a statement released Wednesday through his agent, the 69-year-old performer thanked his fans and said he had had a "wonderful career."
The statement said Hoskins was diagnosed with the degenerative nerve condition last fall.
Hoskins, from Bury St Edmunds in Suffolk, began acting in the late 1960s, and had regular television roles, becoming well-known with the British gangster film The Long Good Friday, alongside Helen Mirren.
In 1986, his portrayal of George in Neil Jordan's film Mona Lisa, about a high-class call girl, won him numerous awards including a Golden Globe for best actor, a BAFTA and an Academy Award nomination.
Hoskins was again nominated for best supporting actor at the Globes for his role in Mrs Henderson Presents, a 2005 British comedy directed by Stephen Frears, starring Dame Judi Dench.
More recently, he took best actor honours at the 2010 International Emmys in the role of a publican in drama The Street.
He also appeared in CBC-TV miniseries The Englishman's Boy, based on the novel by Guy Vanderhaeghe.
Earlier this year he was seen as one of the seven dwarves in Snow White & The Huntsman, starring Kristen Stewart