Debbie Harry, seen here performing at her band Blondie's induction into The Rock and Roll Hall of Fame in March, sang at one of the last shows at pioneering punk club CBGB. ((AP Photo/Jeff Christensen))

Performers and fans alike are in mourning as CBGB, the legendary New York punk-rock club, prepares to close its doors.

This weekend marks the last shows in the club, which will officially close at the end of October.

Blondie singer Deborah Harry, 61,kicked off her Saturday night show with a string of her band’s hits. Harryand her band launched their careers at the club, home to the U.S. punk and new wave movements in the 1970s.

Harry performed an acoustic set with Blondie guitarist Chris Stein on Saturday night, starting with Hanging on the Telephone and the 1980 hit Call Me.

"What are we going to do now? Where are we going to go?" she asked before launching into The Tide Is High and then the Ramones song I Want to Be Your Boyfriend.

Punk poet Patti Smith, who first appeared at the club in 1975, will play the final concert on Sunday night.

Fans heartbroken

After Harry's show, fans stood outside to take photographs of the club’s exterior.

“To see [Harry] play at CBGB’s is like watching her in her backyard —this is her home,” said Greg Adsluf.

The club in Manhattan's East Village lost a protracted fight with its landlord over skyrocketing rent.

Hilly Kristal opened his tiny club in December 1973 under its full name CBGB OMFUG standing for "country, bluegrass, blues and other music for uplifting gormandizers.”

It launched the careers of Blondie, the Cramps, Television, The Ramones and Talking Heads. The Ramones went on to influence British punk bands The Sex Pistols and The Clash.

"Originality [to me] was prime. Technique was secondary," Kristal says on the club’s website.

Steven Van Zandt, of Bruce Springsteen's E Street Band and also an actor in The Sopranos, organized a rally last year to save what he called "the last real rock-and- roll club."

New York Mayor Michael Bloomberg offered to mediate the dispute, describing CBGB's as "a great New York City institution.”

Kristal says he's planning to re-open CBGB in Las Vegas.